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Tg(Sox10-icre/ERT2)388Wdr
Transgene Detail
Summary
Symbol: Tg(Sox10-icre/ERT2)388Wdr
Name: transgene insertion 388, William D Richardson
MGI ID: MGI:5634390
Synonyms: Sox10-iCreERT2, Tg(Sox10-icre/ERT2)#aWdr
Transgene: Tg(Sox10-icre/ERT2)388Wdr  Location: unknown  
Alliance: Tg(Sox10-icre/ERT2)388Wdr page
Transgene
origin
Strain of Origin:  C57BL/6 or CBA
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Tg(Sox10-icre/ERT2)388Wdr expression driven by 1 gene
 
Mutation details: The transgene was generated using the PAC RP21-427F18. Oligodendrocyte-specific expression of the inducible improved cre recombinase (icre/ERT2) was achieved by replacing the coding sequence of Sox10 with the fusion. Four founders were obtained and one (388) was selected for further study. (J:217432)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Sox10 (mouse)
Summary of all recombinase alleles driven by Sox10.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Tumor Data
List all tumor models in MMHCdb carrying Tg(Sox10-icre/ERT2)388Wdr
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:217432 McKenzie IA, et al., Motor skill learning requires active central myelination. Science. 2014 Oct 17;346(6207):318-22
All:  26 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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11/12/2024
MGI 6.24 		The Jackson Laboratory