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Cyp1a1tm1.1(cre)Arte
Targeted Allele Detail
Summary
Symbol: Cyp1a1tm1.1(cre)Arte
Name: cytochrome P450, family 1, subfamily a, polypeptide 1; targeted mutation 1.1, TaconicArtemis
MGI ID: MGI:5635035
Synonyms: CreCyp1a1-KI
Gene: Cyp1a1  Location: Chr9:57595211-57611107 bp, + strand  Genetic Position: Chr9, 31.34 cM
Alliance: Cyp1a1tm1.1(cre)Arte page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:218526
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6N
Mutation
description
Allele Type:    Targeted (Null/knockout, Recombinase)
Mutations:    Insertion, Intragenic deletion
 
Cyp1a1tm1.1(cre)Arte expression driven by 1 gene
 
Mutation details: The coding sequence was replaced with a cre recombinse gene and FRT-flanked neomycin resistance cassette. Flp-mediated recombination removed the selection cassette. (J:218526)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Cyp1a1 (mouse)
Summary of all recombinase alleles driven by Cyp1a1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cyp1a1 Mutation:  39 strains or lines available
References
Original:  J:218526 Henderson CJ, et al., Application of a novel regulatable Cre recombinase system to define the role of liver and gut metabolism in drug oral bioavailability. Biochem J. 2015 Feb 1;465(3):479-88
All:  5 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory