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Pitx2tm2.1Hmd
Targeted Allele Detail
Summary
Symbol: Pitx2tm2.1Hmd
Name: paired-like homeodomain transcription factor 2; targeted mutation 2.1, Hiroshi Hamada
MGI ID: MGI:5636364
Synonyms: Pitx2clacZ
Gene: Pitx2  Location: Chr3:128993527-129013240 bp, + strand  Genetic Position: Chr3, 57.84 cM
Alliance: Pitx2tm2.1Hmd page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:216504
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Reporter)
Mutation:    Insertion
 
Mutation details: A lacZ reporter gene and a FRT-flanked neomycin resistance cassette were inserted into exon 1c. Flp-mediated recombination removed the selection cassette. (J:216504)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Pitx2 Mutation:  40 strains or lines available
References
Original:  J:216504 Shiratori H, et al., Self-regulated left-right asymmetric expression of Pitx2c in the developing mouse limb. Dev Biol. 2014 Nov 15;395(2):331-41
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory