About   Help   FAQ
Col1a1tm2(tetO-GFP/RNAi:Ren)Radi
Targeted Allele Detail
Summary
Symbol: Col1a1tm2(tetO-GFP/RNAi:Ren)Radi
Name: collagen, type I, alpha 1; targeted mutation 2, Ross A Dickins
MGI ID: MGI:5636604
Synonyms: TREtight-GFP-Ren.713
Gene: Col1a1  Location: Chr11:94827050-94843868 bp, + strand  Genetic Position: Chr11, 59.01 cM, cytoband D
Alliance: Col1a1tm2(tetO-GFP/RNAi:Ren)Radi page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:211775
Parent Cell Line:  v6.5 (ES Cell)
Strain of Origin:  (C57BL/6 x 129S4/SvJae)F1
Mutation
description
Allele Type:    Targeted (Knockdown, RMCE-ready)
Mutation:    Insertion
 
Mutation details: RMCE on KH2 cells inserted a cassette that contains the tetracycline promoter and a GFP fusion with an Mir30e-based short hairpin sequence targeting Ren (Ren.713) into the 3'UTR. (J:211775)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Col1a1 Mutation:  163 strains or lines available
Notes
This allele was generated with Col1a1tm13(neo/hygro*)Jae.
References
Original:  J:211775 Liu GJ, et al., Pax5 loss imposes a reversible differentiation block in B-progenitor acute lymphoblastic leukemia. Genes Dev. 2014 Jun 15;28(12):1337-50
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory