Cpt2<tm1b(KOMP)Wtsi> Targeted Allele Detail MGI Mouse (MGI:5636913)

Cpt2^{tm1b(KOMP)Wtsi}
Targeted Allele Detail

Summary

Symbol:	Cpt2^{tm1b(KOMP)Wtsi}
Name:	carnitine palmitoyltransferase 2; targeted mutation 1b, Wellcome Trust Sanger Institute
MGI ID:	MGI:5636913
Gene:	Cpt2 Location: Chr4:107761179-107780786 bp, - strand Genetic Position: Chr4, 50.18 cM
Alliance:	Cpt2^{tm1b(KOMP)Wtsi} page
IMPC:	Cpt2 gene page

Mutation
origin

Mutant Cell Line:	EPD0030_2_H06
Germline Transmission:	Earliest citation of germline transmission: J:204739
Parent Cell Line:	JM8.N4 (ES Cell)
Strain of Origin:	C57BL/6N
Project Collection:	KOMP-CSD

Mutation
description

Allele Type:		Targeted (Null/knockout, Reporter)
Mutations:		Insertion, Intragenic deletion Vector: L1L2_gt2
		Mutation details: Cre-mediated excision of the parental Cpt2^{tm1a(KOMP)Wtsi} allele resulted in the removal of the promoter-driven neomycin selection cassette and critical exon(s) leaving behind the inserted lacZ reporter sequence. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml. (J:204739)

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Expression

In Structures Affected by this Mutation:

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available Cell Lines: 0 lines available
Carrying any Cpt2 Mutation:	27 strains or lines available

References

Original:	J:204739 International Knockout Mouse Consortium, MGI download of modified allele data from IKMC and creation of new knockout alleles. Database Download. 2014-2023;
All:	7 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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