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Aplntm1.1(cre/ERT2)Bzsh
Targeted Allele Detail
Summary
Symbol: Aplntm1.1(cre/ERT2)Bzsh
Name: apelin; targeted mutation 1.1, Bin Zhou
MGI ID: MGI:5637737
Synonyms: Apln-CreER, AplnCreERT2
Gene: Apln  Location: ChrX:47114023-47123730 bp, - strand  Genetic Position: ChrX, 25.48 cM, cytoband A3.2
Alliance: Aplntm1.1(cre/ERT2)Bzsh page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:220957
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Aplntm1.1(cre/ERT2)Bzsh expression driven by 1 gene
 
Mutation details: An inducible cre recombinase fusion (cre/ERT2) and FRT-flanked neomycin resistance cassette replaced the coding sequence in exon 1 from the translation initiation site. Flp-mediated recombination removed the selection cassette. (J:220957)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Apln (mouse)
Summary of all recombinase alleles driven by Apln.
 

Expression
In Mice Carrying this Mutation: 3 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Apln Mutation:  13 strains or lines available
References
Original:  J:220957 Tian X, et al., Subepicardial endothelial cells invade the embryonic ventricle wall to form coronary arteries. Cell Res. 2013 Sep;23(9):1075-90
All:  18 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory