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Gene Expression Data
Assay Details
Assay
Reference: J:96577 Meyer G, et al., Developmental roles of p73 in Cajal-Retzius cells and cortical patterning. J Neurosci. 2004 Nov 3;24(44):9878-87
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5638382
Gene symbol: Calb2
Gene name: calbindin 2
Results
Specimen 4F: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: cortical preplate Present Regionally restricted 4F Expression in pioneer cells in lateral preplate.
TS20: forebrain Present Regionally restricted 4F Expression in basal forebrain.

Specimen 4G: embryonic day 12.0; Trp73tm1Fmc/Trp73tm1Fmc (more )
Structure Level Pattern Image Note
TS20: cortical preplate Present Regionally restricted 4G Expression in increased number of pioneer neurons. Ectopic expression in cells in hem and posteromedial preplate.
TS20: telencephalon Present Regionally restricted 4G Expression in ectopic neurons in the cortical hem.

Specimen data not shown: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: cerebral cortex marginal layer Strong Regionally restricted Intense expression in Cajal-Retzius cells in marginal zone.

Specimen 5E: embryonic day 15.0; Trp73tm1Fmc/Trp73+ (more )
Structure Level Pattern Image Note
TS23: cerebral cortex marginal layer Strong Regionally restricted 5E Intense expression in Cajal-Retzius cells in marginal zone.
TS23: cerebral cortex Present Regionally restricted 5E Expression in pioneer cells above and below cortical plate and thalamocortical fibers terminating in the subplate.

Specimen 5F: embryonic day 15.0; Trp73tm1Fmc/Trp73tm1Fmc (more )
Structure Level Pattern Image Note
TS23: cerebral cortex Present Regionally restricted 5F Expression in pioneer cells above and below cortical plate and thalamocortical fibers terminating in the subplate unchanged in the mutant brain.
TS23: cerebral cortex marginal layer Absent 5F No expression in Cajal-Retzius cells.

Specimen 5G: embryonic day 16.0; Relnrl-Orl/Relnrl-Orl (more )
Structure Level Pattern Image Note
TS24: cerebral cortex Present Regionally restricted 5G Authors report expression in superplate elements.
TS24: cortical plate Present Regionally restricted 5G Expression in aberrant thalamocortical fibers traversing the cortical plate.

Specimen 6A: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: prospective hippocampal fissure Present Regionally restricted 6A Expression in Cajal-Retzius cells occupying prospective hippocampal fissure, which is beginning to fold.
TS23: dentate gyrus primordium Present 6A Expression in dentate primordium ventral to incipient hippocampal fissure.

Specimen 6D: embryonic day 15.0; Trp73tm1Fmc/Trp73tm1Fmc (more )
Structure Level Pattern Image Note
TS23: cerebral cortex marginal layer Absent 6D No expression in Cajal-Retzius cells.

Specimen 9A: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: auditory cortex Present Regionally restricted 9A Laminar expression in interneurons of the auditory and visual areas of cortex.
TS27: visual cortex Present Regionally restricted 9A Laminar expression in interneurons of the auditory and visual areas of cortex.

Specimen 9B: postnatal day 1; E2f1tm1Meg/E2f1tm1Meg (more )
Structure Level Pattern Image Note
TS27: cerebral cortex Present Regionally restricted 9B Expression in interneurons which are distributed differently in mutant compared to wild type cortex.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory