Atg16l1tm1c(EUCOMM)Wtsi
Targeted Allele Detail
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| Symbol: |
Atg16l1tm1c(EUCOMM)Wtsi |
| Name: |
autophagy related 16 like 1; targeted mutation 1c, Wellcome Trust Sanger Institute |
| MGI ID: |
MGI:5638694 |
| Synonyms: |
Agt16l1flox, Atg16l1f |
| Gene: |
Atg16l1 Location: Chr1:87683730-87720150 bp, + strand Genetic Position: Chr1, 44.44 cM
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| Alliance: |
Atg16l1tm1c(EUCOMM)Wtsi page
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| IMPC: |
Atg16l1 gene page |
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| Mutant Cell Line: |
EPD0102_2_A02 |
| Germline Transmission: |
Earliest citation of germline transmission:
J:221019
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| Parent Cell Line: |
JM8.F6 (ES Cell)
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| Strain of Origin: |
C57BL/6N
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| Project Collection: |
EUCOMM
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| Allele Type: |
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Targeted (Conditional ready) |
| Mutation: |
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Insertion
Vector: L1L2_gt2
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Mutation details: The L1L2_gt2 cassette was inserted at position 87692620 of Chromosome 1 upstream of critical exon 3 (Build GRCm39). The cassette is composed of an FRT flanked lacZ/neomycin sequence followed by a loxP site. An additional loxP site is inserted downstream of the targeted exon at position 87693444. Exon 3 is thus flanked by loxP sites. A "conditional ready" (floxed) allele was created by flp recombinase expression in mice carrying this allele.
(J:221019)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Atg16l1 Mutation: |
44 strains or lines available
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| Original: |
J:221019 Conway KL, et al., Atg16l1 is required for autophagy in intestinal epithelial cells and protection of mice from Salmonella infection. Gastroenterology. 2013 Dec;145(6):1347-57 |
| All: |
34 reference(s) |
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Analysis Tools
