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Gene Expression Data
Assay Details
Assay
Reference: J:119270 Zhao Y, et al., Reduced expression of the LIM-homeobox gene Lhx3 impairs growth and differentiation of Rathke's pouch and increases cell apoptosis during mouse pituitary development. Mech Dev. 2006 Aug;123(8):605-13
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5641729
Gene symbol: Lhx3
Gene name: LIM homeobox protein 3
Antibody: 4E12
Detection system: Biotinylated secondary antibody/[Strept]avidin
Results
Specimen 3A: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: Rathke's pouch Strong 3A Expression was abundant.
Specimen 3B: embryonic day 11.5; Lhx3tm1(cre)Slp/Lhx3tm1(cre)Slp (more )
Structure Level Pattern Image Note
TS19: Rathke's pouch Trace 3B
Specimen 3C: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: future spinal cord Present 3C
Specimen 3D: embryonic day 11.5; Lhx3tm1(cre)Slp/Lhx3tm1(cre)Slp (more )
Structure Level Pattern Image Note
TS19: future spinal cord Present 3D Expression was readily detected in the mutant.
Specimen 3E: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: hindbrain Present 3E
Specimen 3F: embryonic day 11.5; Lhx3tm1(cre)Slp/Lhx3tm1(cre)Slp (more )
Structure Level Pattern Image Note
TS19: hindbrain Present 3F Expression was readily detected in the mutant.
Specimen 3G: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: remnant of Rathke's pouch Strong 3G Expression was abundant.
Specimen 3H: embryonic day 12.5; Lhx3tm1(cre)Slp/Lhx3+ (more )
Structure Level Pattern Image Note
TS20: remnant of Rathke's pouch Weak 3H Expression level was reduced to approximately half of that in wild type.
Specimen 3I: embryonic day 12.5; Lhx3tm1(cre)Slp/Lhx3tm1(cre)Slp (more )
Structure Level Pattern Image Note
TS20: remnant of Rathke's pouch Trace 3I
Specimen 3J: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: adenohypophysis Present 3J
Specimen 3K: embryonic day 15.5; Lhx3tm1(cre)Slp/Lhx3+ (more )
Structure Level Pattern Image Note
TS23: adenohypophysis Weak 3K Expression level was reduced to approximately half of that in wild type.
Specimen 3L: embryonic day 15.5; Lhx3tm1(cre)Slp/Lhx3tm1(cre)Slp (more )
Structure Level Pattern Image Note
TS23: adenohypophysis Trace 3L
Specimen 3M: embryonic day 15.5; Lhx3tm1Lmgd/Lhx3+ (more )
Structure Level Pattern Image Note
TS23: adenohypophysis Weak 3M Expression level was reduced to approximately half of that in wild type.
Specimen 3N: embryonic day 15.5; Lhx3tm1Lmgd/Lhx3tm1Lmgd (more )
Structure Level Pattern Image Note
TS23: adenohypophysis Absent 3N
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
MGI 6.13 		The Jackson Laboratory