Col1a1tm2.1(CAG-cre/ERT2)Dgk
Targeted Allele Detail
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| Symbol: |
Col1a1tm2.1(CAG-cre/ERT2)Dgk |
| Name: |
collagen, type I, alpha 1; targeted mutation 2.1, David Kirsch |
| MGI ID: |
MGI:5642281 |
| Synonyms: |
Col1a1FRT-Cre-ER-T2-FRT |
| Gene: |
Col1a1 Location: Chr11:94827050-94843868 bp, + strand Genetic Position: Chr11, 59.01 cM, cytoband D
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| Alliance: |
Col1a1tm2.1(CAG-cre/ERT2)Dgk page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:101977
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| Parent Cell Line: |
Not Specified (ES Cell)
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| Strain of Origin: |
129S4/SvJae
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| Allele Type: |
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Targeted (Conditional ready, Inducible, Recombinase) |
| Inducer: |
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tamoxifen |
| Mutation: |
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Insertion
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Col1a1tm2.1(CAG-cre/ERT2)Dgk expression driven by
1 gene
Knock-in expression driven by:
| Organism |
Driver Gene |
Note |
| chicken |
CAG |
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Mutation details: A targeting vector was designed to insert (from 5 to 3) a CAG promoter, a frt-flanked CreERT2 (Cre recombinase fused to an estrogen receptor ligand binding domain) coding sequence, and an attB/attP-flanked neomycin (neo) resistance cassette downstream of the collagen A1 (Col1a1) promoter. PhiC31-mediated recombination removed the neo cassette.
(J:101977)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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CAG
(chicken)
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| Original: |
J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017; |
| All: |
3 reference(s) |
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Analysis Tools
