Tg(Nos2-tdTomato,-cre)1Albe
Transgene Detail
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| Symbol: |
Tg(Nos2-tdTomato,-cre)1Albe |
| Name: |
transgene insertion 1, Alain Bessis |
| MGI ID: |
MGI:5645754 |
| Synonyms: |
NOS2-Tomato-Cre |
| Transgene: |
Tg(Nos2-tdTomato,-cre)1Albe Location: unknown
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| Alliance: |
Tg(Nos2-tdTomato,-cre)1Albe page
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| Transgene Type: |
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Transgenic (Recombinase, Reporter) |
| Mutation: |
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Insertion
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Tg(Nos2-tdTomato,-cre)1Albe expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Note |
| mouse |
Nos2 (MGI:97361) |
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Mutation details: A tdTomato-IRESs-Cre cassette was inserted by homologous recombination into the RP23-341J22 bacterial artificial chromosome (BAC) that contains 146 kb upstream and 73 kb downstream of the 39kb Nos2 gene. The cassette was inserted into exon 2 with the ATG of the tdTomato replacing the endogenous ATG. The recombined BAC was then used to generate the transgenic mouse. The expression of tdTomato and CRE recombinase faithfully recapitulates the endogenous expression of NOS2.
(J:209609)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Nos2
(mouse)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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| Original: |
J:209609 Bechade C, et al., NOS2 expression is restricted to neurons in the healthy brain but is triggered in microglia upon inflammation. Glia. 2014 Jun;62(6):956-63 |
| All: |
4 reference(s) |
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Analysis Tools
