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Sox1tm3(cre/ERT2)Vep
Targeted Allele Detail
Summary
Symbol: Sox1tm3(cre/ERT2)Vep
Name: SRY (sex determining region Y)-box 1; targeted mutation 3, Vasso Episkopou
MGI ID: MGI:5646006
Synonyms: Sox1CreER, Sox1CreERT2
Gene: Sox1  Location: Chr8:12445519-12449555 bp, + strand  Genetic Position: Chr8, 5.73 cM, cytoband A1-A2
Alliance: Sox1tm3(cre/ERT2)Vep page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:213766
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Sox1tm3(cre/ERT2)Vep expression driven by 1 gene
 
Mutation details: A tamoxifen-inducible fusion cre recombinase gene (cre/ERT2) replaced the coding sequence. An FRT-flanked neomycin resistance cassette was inserted downstream of the fusion gene. (J:213766)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Sox1 (mouse)
Summary of all recombinase alleles driven by Sox1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sox1 Mutation:  13 strains or lines available
References
Original:  J:213766 Kicheva A, et al., Coordination of progenitor specification and growth in mouse and chick spinal cord. Science. 2014 Sep 26;345(6204):1254927
All:  3 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
10/09/2024
MGI 6.24 		The Jackson Laboratory