Tg(Hnrnpa2b1-rtTA2S*M2)9Jstr
Transgene Detail
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| Symbol: |
Tg(Hnrnpa2b1-rtTA2S*M2)9Jstr |
| Name: |
transgene insertion 9, John Strouboulis |
| MGI ID: |
MGI:5648204 |
| Synonyms: |
HNRPA2B1-rtTA2S-M2 |
| Transgene: |
Tg(Hnrnpa2b1-rtTA2S*M2)9Jstr Location: unknown
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| Alliance: |
Tg(Hnrnpa2b1-rtTA2S*M2)9Jstr page
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| Transgene Type: |
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Transgenic (Transactivator) |
| Mutation: |
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Insertion
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Mutation details: The rtTA2S-M2 variant is expressed under the control of the hnRNPA2/B1 promoter. An ~8 kb DNA fragment was used that encompasses the human hnRNPA2/B1-CBX3 gene locus CpG island, which includes two divergently transcribed promoters. Seven transgenic lines were established through transmission of the transgene. Transgenic founder 2 had two integration sites, which separated upon breeding to generate lines 2a and 2b. Line 9 is the highest expressing line in all tissues tested, lines 2a and 2b expressed weakly in some tissues, whereas lines 1, 4, 6 and 7 expressed low but detectable levels. Line 9 was expanded and studied further.
(J:128742)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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| Original: |
J:128742 Katsantoni EZ, et al., Ubiquitous expression of the rtTA2S-M2 inducible system in transgenic mice driven by the human hnRNPA2B1/CBX3 CpG island. BMC Dev Biol. 2007;7:108 |
| All: |
9 reference(s) |
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Analysis Tools
