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Tg(Des-lacZ)#Zli
Transgene Detail
Summary
Symbol: Tg(Des-lacZ)#Zli
Name: transgene insertion, Zhenlin Li
MGI ID: MGI:5648241
Synonyms: Tg(Des-lacZ)Zli/
Transgene: Tg(Des-lacZ)#Zli  Location: unknown  
Alliance: Tg(Des-lacZ)#Zli page
Transgene
origin
Strain of Origin:  (C57BL/6 x DBA/2)F1
Transgene
description
Transgene Type:    Transgenic (Reporter)
Mutation:    Insertion
 
Mutation details: Mdes4kb-lacZ transgenic construct bears a 4.6 kb EcoRI/SalI desmin promoter (from -4005 to +608) and a lacZ reporter gene with a nuclear localization signal. This 4 kb upstream region of the murine desmin promoter directs expression of the LacZ reporter gene throughout the heart from E7.5 and in skeletal muscle and vascular smooth muscle cells from E9.5. Line numbers were not specified. (J:65247)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:65247 Mericskay M, et al., An overlapping CArG/Octamer element is required for regulation of desmin gene transcription in arterial smooth muscle cells. Dev Biol. 2000 Oct 15;226(2):192-208
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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06/12/2024
MGI 6.13 		The Jackson Laboratory