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Atf4tm1(EGFP/Cre/ERT2)Wtsi
Targeted Allele Detail
Summary
Symbol: Atf4tm1(EGFP/Cre/ERT2)Wtsi
Name: activating transcription factor 4; targeted mutation 1, Wellcome Trust Sanger Institute
MGI ID: MGI:5659996
Synonyms: Atf4tm1(EGFP_CreERT2)Wtsi
Gene: Atf4  Location: Chr15:80139385-80141742 bp, + strand  Genetic Position: Chr15, 37.85 cM
Alliance: Atf4tm1(EGFP/Cre/ERT2)Wtsi page
Mutation
origin
Mutant Cell Line:  CEPD0073_2_E06
Germline Transmission:  Earliest citation of germline transmission: J:204812
Parent Cell Line:  JM8.N4 (ES Cell)
Strain of Origin:  C57BL/6N
Project Collection: EUCOMMTOOLS
Mutation
description
Allele Type:    Targeted (Inducible, Recombinase, Reporter)
Inducer:    tamoxifen
Mutation:    Insertion
 
Atf4tm1(EGFP/Cre/ERT2)Wtsi expression driven by 1 gene
 
Mutation details: According the the allele molecular image presented by the International Knockout Mouse Consortium, this allele has one FRT site, an engrailed 2 splice acceptor sequence, an EGFP and cre/ERT2 expression cassette, and a Rox flanked puromycin resistance cassette and a single loxP site inserted after exon 2. (J:157065)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Atf4 (mouse)
Summary of all recombinase alleles driven by Atf4.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Atf4 Mutation:  22 strains or lines available
References
Original:  J:157065 Helmholtz Zentrum Muenchen GmbH, Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu). MGI Direct Data Submission. 2010-2015;
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory