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Pla2g2etm1.1Murm
Targeted Allele Detail
Summary
Symbol: Pla2g2etm1.1Murm
Name: phospholipase A2, group IIE; targeted mutation 1.1, Makoto Murakami
MGI ID: MGI:5660236
Gene: Pla2g2e  Location: Chr4:138605253-138610125 bp, + strand  Genetic Position: Chr4, 70.57 cM
Alliance: Pla2g2etm1.1Murm page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:215319
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA loxP site and FRT flanked neo cassette were inserted upstream of exon 3 and a loxP site was inserted downstream of exon 4 via homologous recombination. Cre mediated recombination removed the neo cassette and exons 3 and 4. (J:215319)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pla2g2e Mutation:  13 strains or lines available
References
Original:  J:215319 Sato H, et al., The adipocyte-inducible secreted phospholipases PLA2G5 and PLA2G2E play distinct roles in obesity. Cell Metab. 2014 Jul 1;20(1):119-32
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory