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Gene Expression Data
Assay Details
Assay
Reference: J:96501 Sasaki T, et al., LEF1 is a critical epithelial survival factor during tooth morphogenesis. Dev Biol. 2005 Feb 1;278(1):130-43
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5661450
Gene symbol: Rb1
Gene name: RB transcriptional corepressor 1
Antibody: anti-phospho-Rb
Detection system: Secondary antibody
Assay notes: The antibody used recognizes the phosphorylated form of the protein.
Results
Specimen 6A: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: tooth Present 6A
Specimen 6B: embryonic day 13.5; Lef1tm1Rug/Lef1tm1Rug (more )
Structure Level Pattern Image Note
TS21: tooth Present 6B Normal expression as in wild-type.
Specimen 6C: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: tooth epithelium Present 6C
TS22: tooth mesenchyme Present Regionally restricted 6C Expressed in the cranial neural crest-derived mesenchyme.
Specimen 6D: embryonic day 14.5; Lef1tm1Rug/Lef1tm1Rug (more )
Structure Level Pattern Image Note
TS22: tooth epithelium Present 6D Comparable expression as in wild-type.
TS22: tooth mesenchyme Present Regionally restricted 6D Comparable expression as in wild-type. Expressed in the cranial neural crest-derived mesenchyme.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
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