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Tg(HCRT-EGFP,-cre)1Ahky
Transgene Detail
Summary
Symbol: Tg(HCRT-EGFP,-cre)1Ahky
Name: transgene insertion 1, Akihiro Yamanaka
MGI ID: MGI:5662280
Synonyms: orexin-Cre, Tg(HCRT-EGFP,-cre)#aAhky
Transgene: Tg(HCRT-EGFP,-cre)1Ahky  Location: unknown  
Alliance: Tg(HCRT-EGFP,-cre)1Ahky page
Transgene
origin
Strain of Origin:  C57BL/6J
Transgene
description
Transgene Type:    Transgenic (Recombinase, Reporter)
Mutation:    Insertion
 
Tg(HCRT-EGFP,-cre)1Ahky expression driven by 1 gene
 
Mutation details: A 3.2 kb fragment of the human promoter drives orexin neurons-specific expression of EGFP and cre recombinase gene separated by a 2A peptide sequence and followed by a murine Prm1 gene intron and polyadenylation sequence. Two lines were generated with the unnamed line #a having with the highest expression. (J:215679)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: HCRT (human)
Summary of all recombinase alleles driven by HCRT.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:215679 Inutsuka A, et al., Concurrent and robust regulation of feeding behaviors and metabolism by orexin neurons. Neuropharmacology. 2014 Oct;85:451-60
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory