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Myf6tm1.1(cre/Esr1*)Cklr
Targeted Allele Detail
Summary
Symbol: Myf6tm1.1(cre/Esr1*)Cklr
Name: myogenic factor 6; targeted mutation 1.1, Charles Keller
MGI ID: MGI:5688769
Synonyms: Myf6CreER
Gene: Myf6  Location: Chr10:107328709-107330584 bp, - strand  Genetic Position: Chr10, 55.96 cM
Alliance: Myf6tm1.1(cre/Esr1*)Cklr page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:214957
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Myf6tm1.1(cre/Esr1*)Cklr expression driven by 1 gene
 
Mutation details: Homologous recombination in ES cells inserted an IRES-creERTM-FRT-Neo-FRT sequence into the 3' UTR following the stop codon in exon 3. Flp-mediated recombination removed the selection cassette. (J:214957)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Myf6 (mouse)
Summary of all recombinase alleles driven by Myf6.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Myf6 Mutation:  19 strains or lines available
References
Original:  J:214957 Abraham J, et al., Lineage of origin in rhabdomyosarcoma informs pharmacological response. Genes Dev. 2014 Jul 15;28(14):1578-91
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory