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Fgf8tm1(cre/ERT2)Jlr
Targeted Allele Detail
Summary
Symbol: Fgf8tm1(cre/ERT2)Jlr
Name: fibroblast growth factor 8; targeted mutation 1, John Rubenstein
MGI ID: MGI:5690222
Synonyms: Fgf8CreER
Gene: Fgf8  Location: Chr19:45725237-45731354 bp, - strand  Genetic Position: Chr19, 38.75 cM, cytoband C3-D
Alliance: Fgf8tm1(cre/ERT2)Jlr page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:222259
Parent Cell Line:  PRX-B6T (ES Cell)
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Targeted (Inducible, Recombinase)
Inducer:    tamoxifen
Mutations:    Insertion, Intragenic deletion
 
Fgf8tm1(cre/ERT2)Jlr expression driven by 1 gene
 
Mutation details: An inducible cre recombinase gene (cre/ERT2), polyadenylation sequence and floxed neomycin resistance cassette replace the coding sequence in exon 1. (J:222259)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Fgf8 (mouse)
Summary of all recombinase alleles driven by Fgf8.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Fgf8 Mutation:  21 strains or lines available
References
Original:  J:222259 Hoch RV, et al., Fgf signaling controls the telencephalic distribution of Fgf-expressing progenitors generated in the rostral patterning center. Neural Dev. 2015;10:8
All:  4 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory