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Gene Expression Data
Assay Details
Assay
Reference: J:199400 van den Heuvel DM, et al., Spatiotemporal expression of repulsive guidance molecules (RGMs) and their receptor neogenin in the mouse brain. PLoS One. 2013;8(2):e55828
Assay type: RNA in situ
MGI Accession ID: MGI:5693259
Gene symbol: Unc5c
Gene name: unc-5 netrin receptor C
Probe: Unc5c cDNA1
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 2C: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: main olfactory bulb mitral cell layer Present Regionally restricted 2C Expression was detected a small subset of dorsal mitral cells.
TS24: ethmoid bone cribriform plate Present 2C
TS24: main olfactory bulb prospective granule cell layer Present 2C

Specimen 2G: postnatal day 5 (more )
Structure Level Pattern Image Note
TS28: main olfactory bulb glomerular layer Present 2G Expression was reduced compared to E16.5.
TS28: main olfactory bulb granule cell layer Present 2G Expression was reduced compared to E16.5.
TS28: main olfactory bulb mitral cell layer Present 2G Expression was reduced compared to E16.5.

Specimen Table S2 E16.5: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: main olfactory bulb ventricular layer Absent
TS24: olfactory epithelium Absent
TS24: ethmoid bone cribriform plate Very strong
TS24: accessory olfactory bulb Moderate
TS24: main olfactory bulb internal plexiform layer Moderate
TS24: main olfactory bulb external plexiform layer Weak
TS24: main olfactory bulb prospective glomerular layer Weak
TS24: main olfactory bulb mitral cell layer Strong
TS24: main olfactory bulb prospective granule cell layer Strong

Specimen Table S2 P5: postnatal day 5 (more )
Structure Level Pattern Image Note
TS28: main olfactory bulb glomerular layer Weak
TS28: main olfactory bulb granule cell layer Weak
TS28: main olfactory bulb external plexiform layer Absent
TS28: main olfactory bulb internal plexiform layer Absent
TS28: olfactory epithelium Absent
TS28: anterior olfactory nucleus Moderate
TS28: ethmoid bone cribriform plate Moderate
TS28: main olfactory bulb mitral cell layer Moderate
TS28: main olfactory bulb ventricular layer Moderate

Specimen Table S2 Adult: postnatal adult (more )
Structure Level Pattern Image Note
TS28: main olfactory bulb glomerular layer Weak
TS28: main olfactory bulb granule cell layer Weak
TS28: main olfactory bulb external plexiform layer Absent
TS28: main olfactory bulb internal plexiform layer Absent
TS28: main olfactory bulb mitral cell layer Moderate
TS28: main olfactory bulb ventricular layer Moderate
TS28: anterior olfactory nucleus Strong

Specimen 5C: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: cerebral cortex subventricular zone Present 5C
TS24: cerebral cortex ventricular layer Present 5C
TS24: cortical plate Present 5C
TS24: cortical subplate Present 5C

Specimen 5G: postnatal day 5 (more )
Structure Level Pattern Image Note
TS28: cerebral cortex Present Widespread 5G

Specimen Table S3 E16.5: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: cerebral cortex intermediate zone Absent
TS24: cerebral cortex marginal layer Absent
TS24: telencephalon pia mater Absent
TS24: cortical plate Moderate
TS24: cortical subplate Strong
TS24: cerebral cortex subventricular zone Weak
TS24: cerebral cortex ventricular layer Weak

Specimen Table S3 P5: postnatal day 5 (more )
Structure Level Pattern Image Note
TS28: cortical layer I Moderate
TS28: cortical layer II Moderate
TS28: cortical layer IV Moderate
TS28: cortical layer V Moderate
TS28: cortical layer III Strong
TS28: cortical layer VI Absent
TS28: cerebral cortex ventricular zone Weak

Specimen Table S3 Adult: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cerebral cortex ventricular zone Absent
TS28: cortical layer I Absent
TS28: cortical layer II Absent
TS28: cortical layer III Absent
TS28: cortical layer IV Absent
TS28: cortical layer VI Absent
TS28: cortical layer V Weak

Specimen 7C: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: hippocampus Present Regionally restricted 7C Expression was detected in the CA region.
TS24: dentate gyrus primordium Present 7C

Specimen 7G: postnatal day 5 (more )
Structure Level Pattern Image Note
TS28: dentate gyrus Present 7G
TS28: hippocampus CA1 Present 7G
TS28: hippocampus CA2 Present 7G
TS28: hippocampus CA3 Present 7G

Specimen Table S4 E16.5: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: hippocampus Weak Regionally restricted Weak expression was detected in the CA region and the subventricular zone.
TS24: dentate gyrus primordium Moderate
TS24: entorhinal cortex Absent
TS24: hippocampus ventricular layer Weak

Specimen Table S4 P5: postnatal day 5 (more )
Structure Level Pattern Image Note
TS28: hippocampus CA1 Weak
TS28: hippocampus CA2 Weak
TS28: hippocampus CA3 Strong
TS28: dentate gyrus Weak
TS28: dentate gyrus granule cell layer Weak
TS28: dentate gyrus molecular layer Weak
TS28: dentate gyrus polymorphic layer Weak
TS28: entorhinal cortex Absent
TS28: hippocampus stratum lacunosum Absent
TS28: hippocampus stratum oriens Absent
TS28: hippocampus stratum radiatum Absent

Specimen Table S4 Adult: postnatal adult (more )
Structure Level Pattern Image Note
TS28: hippocampus CA1 Weak
TS28: hippocampus CA2 Moderate
TS28: hippocampus CA3 Strong
TS28: dentate gyrus Moderate
TS28: dentate gyrus granule cell layer Moderate
TS28: dentate gyrus polymorphic layer Weak
TS28: dentate gyrus molecular layer Absent
TS28: entorhinal cortex Absent
TS28: hippocampus stratum lacunosum Absent
TS28: hippocampus stratum oriens Absent
TS28: hippocampus stratum radiatum Absent

Specimen 10C: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: lateral habenular nucleus Present 10C

Specimen 10G: postnatal day 5 (more )
Structure Level Pattern Image Note
TS28: habenula Absent 10G

Specimen 10K: postnatal adult (more )
Structure Level Pattern Image Note
TS28: habenula Absent 10K

Specimen Table S5 E16.5: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: midbrain Moderate Regionally restricted Expression was detected in the substantia nigra and the ventral tegmental area.
TS24: corpus striatum Moderate
TS24: lateral habenular nucleus Moderate
TS24: telencephalon septum Moderate
TS24: interpeduncular nucleus Strong
TS24: thalamus Strong
TS24: hypothalamus Strong Regionally restricted Expression was strong in the lateral hypothalamus.
TS24: medial habenular nucleus Absent

Specimen Table S5 P5: postnatal day 5 (more )
Structure Level Pattern Image Note
TS28: corpus striatum Absent
TS28: hypothalamus lateral zone Absent
TS28: interpeduncular nucleus Absent
TS28: lateral habenular nucleus Absent
TS28: medial habenular nucleus Absent
TS28: telencephalon septum Absent
TS28: paraventricular thalamic nucleus Moderate
TS28: substantia nigra Moderate
TS28: thalamus Moderate
TS28: ventral tegmental area Moderate

Specimen Table S5 Adult: postnatal adult (more )
Structure Level Pattern Image Note
TS28: corpus striatum Absent
TS28: hypothalamus lateral zone Absent
TS28: interpeduncular nucleus Absent
TS28: lateral habenular nucleus Absent
TS28: medial habenular nucleus Absent
TS28: substantia nigra Absent
TS28: telencephalon septum Absent
TS28: ventral tegmental area Absent
TS28: paraventricular thalamic nucleus Moderate
TS28: thalamus Moderate

Specimen 13C: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: cerebellum external granule cell layer Present 13C

Specimen 13G: postnatal day 5 (more )
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Present 13G
TS28: cerebellum external granule cell layer Present 13G
TS28: cerebellum internal granule cell layer Present 13G

Specimen Table S6 E16.5: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: cerebellum ventricular layer Very strong
TS24: deep cerebellar nucleus Very strong
TS24: cerebellum Purkinje cell cluster Strong
TS24: cerebellum external granule cell layer Strong

Specimen Table S6 P5: postnatal day 5 (more )
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Strong
TS28: cerebellum external granule cell layer Strong
TS28: cerebellum internal granule cell layer Strong

Specimen Table S6 Adult: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Strong
TS28: cerebellum granule cell layer Strong
TS28: cerebellum molecular layer Absent


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory