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Npwtm1.1(icre)Ymf
Targeted Allele Detail
Summary
Symbol: Npwtm1.1(icre)Ymf
Name: neuropeptide W; targeted mutation 1.1, Masa Fu Yanagisawa
MGI ID: MGI:5694675
Synonyms: NPW-iCre
Gene: Npw  Location: Chr17:24876304-24877431 bp, - strand  Genetic Position: Chr17, 12.45 cM
Alliance: Npwtm1.1(icre)Ymf page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:225431
Parent Cell Line:  RENKA (ES Cell)
Strain of Origin:  C57BL/6N
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Npwtm1.1(icre)Ymf expression driven by 1 gene
 
Mutation details: An improved cre recombinase gene and FRT-flanked neomycin resistance cassette were inserted at the translation initiation sequence in exon 1. Flp-mediated recombination removed the selection cassette. (J:225431)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Npw (mouse)
Summary of all recombinase alleles driven by Npw.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Npw Mutation:  9 strains or lines available
References
Original:  J:225431 Motoike T, et al., Transient expression of neuropeptide W in postnatal mouse hypothalamus--a putative regulator of energy homeostasis. Neuroscience. 2015 Aug 20;301:323-37
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory