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Wdr13tm1Kuma
Targeted Allele Detail
Summary
Symbol: Wdr13tm1Kuma
Name: WD repeat domain 13; targeted mutation 1, Satish Kumar
MGI ID: MGI:5694710
Gene: Wdr13  Location: ChrX:7989540-7999131 bp, - strand  Genetic Position: ChrX, 3.67 cM, cytoband A1.1
Alliance: Wdr13tm1Kuma page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:225111
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details: A neomycin resistance cassette replaced exon 2 and intron 2. Western blot analysis confirmed the absence of protein in testis and brain. (J:225111)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 6 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Wdr13 Mutation:  11 strains or lines available
References
Original:  J:225111 Singh VP, et al., Lack of Wdr13 gene in mice leads to enhanced pancreatic beta cell proliferation, hyperinsulinemia and mild obesity. PLoS One. 2012;7(6):e38685
All:  6 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory