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Btg2tm1.1(cre/ERT2)Wbh
Targeted Allele Detail
Summary
Symbol: Btg2tm1.1(cre/ERT2)Wbh
Name: BTG anti-proliferation factor 2; targeted mutation 1.1, Weiland B Huttner
MGI ID: MGI:5696980
Synonyms: Tis21-CreERT2
Gene: Btg2  Location: Chr1:134002908-134006858 bp, - strand  Genetic Position: Chr1, 58.1 cM
Alliance: Btg2tm1.1(cre/ERT2)Wbh page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:225790
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Inducible, Recombinase)
Inducer:    tamoxifen
Mutations:    Insertion, Intragenic deletion
 
Btg2tm1.1(cre/ERT2)Wbh expression driven by 1 gene
 
Mutation details: The targeting construct replaced exon 1 with an inducible cre recombinase gene (cre/ERT2), polyadenylation sequence, HSV tag and FRT-flanked neomycin resistance cassette. Flp-mediated recombination removed the selection cassette. (J:225790)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Btg2 (mouse)
Summary of all recombinase alleles driven by Btg2.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Btg2 Mutation:  16 strains or lines available
References
Original:  J:225790 Wong FK, et al., Sustained Pax6 Expression Generates Primate-like Basal Radial Glia in Developing Mouse Neocortex. PLoS Biol. 2015 Aug;13(8):e1002217
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory