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Pde6gtm1(cre/ERT2)Eye
Targeted Allele Detail
Summary
Symbol: Pde6gtm1(cre/ERT2)Eye
Name: phosphodiesterase 6G, cGMP-specific, rod, gamma; targeted mutation 1, Stephen H Tsang
MGI ID: MGI:5696992
Synonyms: Pde6gCreERT2
Gene: Pde6g  Location: Chr11:120338433-120344326 bp, - strand  Genetic Position: Chr11, 84.14 cM
Alliance: Pde6gtm1(cre/ERT2)Eye page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:226244
Parent Cell Line:  KV1 (ES Cell)
Strain of Origin:  (C57BL/6J x 129S6/SvEvTac)F1
Mutation
description
Allele Type:    Targeted (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Pde6gtm1(cre/ERT2)Eye expression driven by 1 gene
    An inducible cre recombinase gene (cre/ERT2) and neomycin resistance cassette replaced exon 2 and 3. (J:226244)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Pde6g (mouse)
Summary of all recombinase alleles driven by Pde6g.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pde6g Mutation:  11 strains or lines available
References
Original:  J:226244 Koch SF, et al., Halting progressive neurodegeneration in advanced retinitis pigmentosa. J Clin Invest. 2015 Sep;125(9):3704-13
All:  9 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory