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Mir203tm1.1Yir
Targeted Allele Detail
Summary
Symbol: Mir203tm1.1Yir
Name: microRNA 203; targeted mutation 1.1, Rui Yi
MGI ID: MGI:5698058
Synonyms: niR-203fl
Gene: Mir203  Location: Chr12:112097314-112097389 bp, + strand  Genetic Position: Chr12, 61.14 cM
Alliance: Mir203tm1.1Yir page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:226044
Parent Cell Line:  CY2.4 (ES Cell)
Strain of Origin:  B6(Cg)-Tyrc-2J
Mutation
description
Allele Type:    Targeted (Conditional ready)
Mutation:    Insertion
 
Mutation details: The targeting constructs contains a loxP site upstream of the Mir203 hairpin loop and a FRT-flanked neomycin cassette followed by a loxP site downstream of the hairpin loop. Flp-mediated recombination removed the FRT-flanked neo cassette. (J:226044)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Mir203 Mutation:  4 strains or lines available
References
Original:  J:226044 Riemondy K, et al., MicroRNA-203 represses selection and expansion of oncogenic Hras transformed tumor initiating cells. Elife. 2015;4
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory