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Gene Expression Data
Assay Details
Assay
Reference: J:226614 Costello I, et al., Lhx1 functions together with Otx2, Foxa2, and Ldb1 to govern anterior mesendoderm, node, and midline development. Genes Dev. 2015 Oct 15;29(20):2108-22
Assay type: RNA in situ
MGI Accession ID: MGI:5701426
Gene symbol: Nodal
Gene name: nodal growth differentiation factor
Probe: Nodal probe18
Probe preparation: Antisense RNA
Results
Specimen 4E Control: embryonic day 8.0 (more )
Structure Level Pattern Image Note
TS12: node Present Non-Uniform 4E Control Expression is asymmetric and left-sided.
Specimen 4E Mutant: embryonic day 8.0; Lhx1tm1Bhr/Lhx1tm2.1Rob, Edil3Tg(Sox2-cre)1Amc/Edil3+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS12: node Present 4E Lhx1 delta Epi Unlike the asymmetric, left-sided expression seen in wild-type embryos, bilateral, right-sided, and ectopic expression is seen in the mutant node.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
MGI 6.13 		The Jackson Laboratory