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Col1a1tm16(tetO-GFP/RNAi:Trim33)Slowe
Targeted Allele Detail
Summary
Symbol: Col1a1tm16(tetO-GFP/RNAi:Trim33)Slowe
Name: collagen, type I, alpha 1; targeted mutation 16, Scott Lowe
MGI ID: MGI:5750939
Gene: Col1a1  Location: Chr11:94827050-94843868 bp, + strand  Genetic Position: Chr11, 59.01 cM, cytoband D
Alliance: Col1a1tm16(tetO-GFP/RNAi:Trim33)Slowe page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:221105
Parent Cell Line:  v6.5 (ES Cell)
Strain of Origin:  (C57BL/6 x 129S4/SvJae)F1
Mutation
description
Allele Type:    Targeted (Inducible, Knockdown, RMCE-ready, Reporter)
Inducer:    doxycycline/tetracycline
Mutation:    Insertion
  Col1a1tm16(tetO-GFP/RNAi:Trim33)Slowe involves 1 genes/genome features (Trim33) View all
 
Mutation details: RMCE on KH2 cells inserted a cassette that contains the tetracycline promoter and a GFP fusion with an Mir30e-based short hairpin sequence targeting Trim33 into the 3'UTR. (J:221105)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Col1a1 Mutation:  163 strains or lines available
Notes
This allele was generated with Col1a1tm13(neo/hygro*)Jae.
References
Original:  J:221105 Wang E, et al., The transcriptional cofactor TRIM33 prevents apoptosis in B lymphoblastic leukemia by deactivating a single enhancer. Elife. 2015;4
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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11/12/2024
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