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Pirbtm2Stz
Targeted Allele Detail
Summary
Symbol: Pirbtm2Stz
Name: paired Ig-like receptor B; targeted mutation 2, Carla J Shatz
MGI ID: MGI:5751411
Synonyms: PirB flox
Gene: Pirb  Location: Chr7:3715504-3723381 bp, - strand  Genetic Position: Chr7, 2.14 cM
Alliance: Pirbtm2Stz page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:225778
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Conditional ready)
Mutation:    Insertion
 
Mutation details: A loxP site was inserted upstream of exon 10. An FRT and loxP site was inserted downstream of exon 13. This allele was used to generate Pirbtm2Stz. (J:225778)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pirb Mutation:  65 strains or lines available
References
Original:  J:225778 Bochner DN, et al., Blocking PirB up-regulates spines and functional synapses to unlock visual cortical plasticity and facilitate recovery from amblyopia. Sci Transl Med. 2014 Oct 15;6(258):258ra140
All:  4 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory