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Atoh1tm1(cre)Jbr
Targeted Allele Detail
Summary
Symbol: Atoh1tm1(cre)Jbr
Name: atonal bHLH transcription factor 1; targeted mutation 1, Jean-Francois Brunet
MGI ID: MGI:5751764
Synonyms: Atoh1FRTCre
Gene: Atoh1  Location: Chr6:64706109-64708229 bp, + strand  Genetic Position: Chr6, 30.03 cM
Alliance: Atoh1tm1(cre)Jbr page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:229254
Parent Cell Line:  BD10 (ES Cell)
Strain of Origin:  C57BL/6NTac
Mutation
description
Allele Type:    Targeted (Conditional ready, Recombinase)
Mutation:    Insertion
 
Atoh1tm1(cre)Jbr expression driven by 1 gene
 
Mutation details: The targeting construct inserted into the 3' UTR downstream of the stop codon an FRT-flanked neomycin resistance cassette, IRES sequence, cre recombinase gene and bovine growth hormone polyadenylation sequence. (J:229254)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Atoh1 (mouse)
Summary of all recombinase alleles driven by Atoh1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Atoh1 Mutation:  37 strains or lines available
References
Original:  J:229254 Ruffault PL, et al., The retrotrapezoid nucleus neurons expressing Atoh1 and Phox2b are essential for the respiratory response to CO(2). Elife. 2015;4
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory