Raet1e<em1Dhr> Endonuclease-mediated Allele Detail MGI Mouse (MGI:5752306)

About Help FAQ

Raet1e^em1Dhr
Endonuclease-mediated Allele Detail

Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Summary

Symbol:	Raet1e^em1Dhr
Name:	retinoic acid early transcript 1E; endonuclease-mediated mutation 1, David H Raulet
MGI ID:	MGI:5752306
Gene:	Raet1e Location: Chr10:22034441-22059820 bp, + strand Genetic Position: Chr10, 9.89 cM
Alliance:	Raet1e^em1Dhr page

Mutation
origin

Strain of Origin:

C57BL/6

Mutation
description

Allele Type:		Endonuclease-mediated (Null/knockout)
Mutation:		Intragenic deletion
		Mutation details: CRISPR/Cas9 was used to induce a frameshift mutation in exon 2. Mutations were created in cis in both this gene and Raet1d, Raet1d^em1Dhr (J:221188)

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Raet1e Mutation:	13 strains or lines available

References

Original:	J:221188 Deng W, et al., Antitumor immunity. A shed NKG2D ligand that promotes natural killer cell activation and tumor rejection. Science. 2015 Apr 3;348(6230):136-9
All:	2 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/19/2024 MGI 6.24