Antxr1tm1Bjro
Targeted Allele Detail
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| Symbol: |
Antxr1tm1Bjro |
| Name: |
anthrax toxin receptor 1; targeted mutation 1, Bjorn R Olsen |
| MGI ID: |
MGI:5754386 |
| Synonyms: |
Antrx1KI |
| Gene: |
Antxr1 Location: Chr6:87110835-87312757 bp, - strand Genetic Position: Chr6, 37.94 cM
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| Alliance: |
Antxr1tm1Bjro page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:224431
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| Parent Cell Line: |
GermLine mESC C57BL6/129SvJ, ASE-9005 (ES Cell)
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| Strain of Origin: |
(C57BL/6 x 129X1/SvJ)F1
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| Allele Type: |
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Targeted (Not Applicable) |
| Mutations: |
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Insertion, Intragenic deletion, Single point mutation
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Mutation details: Exons 12 and 13 were fused and a G to A point mutation in exon 13 results in the amino acid substitution of threonine for alanine at position 324 (A324T). An FRT-flanked neomycin resistance cassette with a 5' loxP site was inserted upstream of exon 12.
(J:224431)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Antxr1 Mutation: |
29 strains or lines available
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| Original: |
J:224431 Besschetnova TY, et al., Regulatory mechanisms of anthrax toxin receptor 1-dependent vascular and connective tissue homeostasis. Matrix Biol. 2015 Mar;42:56-73 |
| All: |
1 reference(s) |
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Analysis Tools
