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Gene Expression Data
Assay Details
Assay
Reference: J:61486 Littlewood Evans A, et al., Stereocilia defects in the sensory hair cells of the inner ear in mice deficient in integrin alpha8beta1. Nat Genet. 2000 Apr;24(4):424-8
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5755635
Gene symbol: Calb2
Gene name: calbindin 2
Antibody: anti-calretinin
Detection system: Secondary antibody coupled to fluorescein
Results
Specimen 2a +/-: postnatal day 0; Itga8tm1Lfr/Itga8+ (more )
Structure Level Pattern Image Note
TS27: utricle epithelium Present Regionally restricted 2a +/- Expression is in hair cells.

Specimen 2a -/-: postnatal day 0; Itga8tm1Lfr/Itga8tm1Lfr (more )
Structure Level Pattern Image Note
TS27: utricle epithelium Present Regionally restricted 2a -/- Expression is in hair cells.

Specimen 2b +/-: postnatal day 0; Itga8tm1Lfr/Itga8+ (more )
Note: Double labeled: green -Calb2; red - F-actin.
Structure Level Pattern Image Note
TS27: utricle epithelium Present Regionally restricted 2b cal +/- , 2b +/- Expression is in hair cells.

Specimen 2b -/-: postnatal day 0; Itga8tm1Lfr/Itga8tm1Lfr (more )
Note: Double labeled: green -Calb2; red - F-actin.
Structure Level Pattern Image Note
TS27: utricle epithelium Present Regionally restricted 2b -/- , 2b cal -/- Expression is in hair cells.

Specimen 2d -/- saccule: postnatal day 0; Itga8tm1Lfr/Itga8tm1Lfr (more )
Note: Double labeled: green -Calb2; red - F-actin.
Structure Level Pattern Image Note
TS27: saccule epithelium Present Regionally restricted 2d cal -/- saccule , 2d -/- saccule Expression is in hair cells.

Specimen 2d -/- crista: postnatal day 0; Itga8tm1Lfr/Itga8tm1Lfr (more )
Note: Double labeled: green -Calb2; red - F-actin.
Structure Level Pattern Image Note
TS27: crista ampullaris Present Regionally restricted 2d -/- crista , 2d cal -/- crista Expression is in hair cells.

Specimen 2e +/-: embryonic day 18.0; Itga8tm1Lfr/Itga8+ (more )
Note: Double labeled: green -Calb2; red - F-actin.
Structure Level Pattern Image Note
TS26: utricle epithelium Present Regionally restricted 2e +/- Expression is in hair cells.

Specimen 2e left: embryonic day 18.0; Itga8tm1Lfr/Itga8tm1Lfr (more )
Note: Double labeled: green -Calb2; red - F-actin.
Structure Level Pattern Image Note
TS26: utricle epithelium Present Regionally restricted 2e -/- left Expression is in hair cells.

Specimen 2e right: embryonic day 18.0; Itga8tm1Lfr/Itga8tm1Lfr (more )
Note: Double labeled: green -Calb2; red - F-actin.
Structure Level Pattern Image Note
TS26: utricle epithelium Present Regionally restricted 2e -/- right Expression is in hair cells.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory