Tg(Mbp-icre/ERT2)#Rjfl
Transgene Detail
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| Symbol: |
Tg(Mbp-icre/ERT2)#Rjfl |
| Name: |
transgene insertion, Robin JM Franklin |
| MGI ID: |
MGI:5763089 |
| Synonyms: |
Mbp-iCreERT2 |
| Transgene: |
Tg(Mbp-icre/ERT2)#Rjfl Location: unknown
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| Alliance: |
Tg(Mbp-icre/ERT2)#Rjfl page
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| Transgene Type: |
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Transgenic (Inducible, Recombinase) |
| Inducer: |
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tamoxifen |
| Mutation: |
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Insertion
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Tg(Mbp-icre/ERT2)#Rjfl expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Note |
| Not Specified |
Mbp |
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Mutation details: The transgenic mouse strain was made using small plasmid transgenesis. A 5.89-Kbp upstream region of Mbp (promoter fragment) was used for driving iCreERT2 with parts of Plp exons 6 and 7 downstream, followed by a poly(A) sequence. Two founders were obtained, and as both had similar expression patterns and intensity, one was selected for further characterization. Line numbers were not indicated. The pound symbol (#) is used when no line is specified and/or lines are pooled.
(J:229987)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Mbp
(species not specified)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:229987 Crawford AH, et al., Pre-Existing Mature Oligodendrocytes Do Not Contribute to Remyelination following Toxin-Induced Spinal Cord Demyelination. Am J Pathol. 2016 Mar;186(3):511-6 |
| All: |
1 reference(s) |
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Analysis Tools
