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Gng7tm1.1(EGFP/cre/ERT2)Wtsi
Targeted Allele Detail
Summary
Symbol: Gng7tm1.1(EGFP/cre/ERT2)Wtsi
Name: guanine nucleotide binding protein (G protein), gamma 7; EUCOMM targeted mutation 1.1, Wellcome Trust Sanger Institute
MGI ID: MGI:5766130
Gene: Gng7  Location: Chr10:80784463-80850742 bp, - strand  Genetic Position: Chr10, 39.72 cM
Mutation
origin
Mutant Cell Lines:  CEPD0001_1_A03, CEPD0001_1_A04, CEPD0001_1_B01, CEPD0001_1_B02, CEPD0001_1_B03, CEPD0001_1_B04, CEPD0001_1_C03, CEPD0001_1_D02, CEPD0001_1_D03, CEPD0001_1_D04, CEPD0001_1_E04, CEPD0001_1_F01, CEPD0001_1_G03, CEPD0001_1_G04, CEPD0001_1_H02, CEPD0001_1_H03, CEPD0001_1_H04, CEPD0001_5_A01, CEPD0001_5_A02, CEPD0001_5_A03, CEPD0001_5_A04, CEPD0001_5_B03, CEPD0001_5_B06, CEPD0001_5_C05, CEPD0001_5_C06, CEPD0001_5_D02, CEPD0001_5_E04, CEPD0001_5_F02, CEPD0001_5_G03, CEPD0001_5_H03, CEPD0001_5_H04, CEPD0001_5_H05, CEPD0001_5_H06
Germline Transmission:  Unknown
Parent Cell Line:  JM8.N4 (ES Cell)
Strain of Origin:  C57BL/6N
Project Collection: EUCOMMTOOLS
Mutation
description
Allele Type:    Targeted (Inducible, Recombinase, Reporter)
Inducer:    tamoxifen
Mutation:    Insertion
 
Gng7tm1.1(EGFP/cre/ERT2)Wtsi expression driven by 1 gene
 
Mutation details: According to the allele molecular image presented by the International Knockout Mouse Consortium, this allele has loxP sites flanking exon 4, and inserted into the intron between exons 3 and 4 is one FRT site, an engrailed 2 splice acceptor sequence, and an EGFP and cre/ERT2 expression cassette. A Rox flanked puromycin resistance cassette was deleted in ES cell with dre recombinase and exon 4 was deleted via cre recombinase. (J:155845)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Gng7 (mouse)
Summary of all recombinase alleles driven by Gng7.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gng7 Mutation:  75 strains or lines available
References
Original:  J:155845 Wellcome Trust Sanger Institute, Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute. MGI Direct Data Submission. 2010;
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory