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P2ry1tm1.1(cre)Lbrl
Targeted Allele Detail
Summary
Symbol: P2ry1tm1.1(cre)Lbrl
Name: purinergic receptor P2Y, G-protein coupled 1; targeted mutation 1.1, Stephen Liberles
MGI ID: MGI:5776536
Synonyms: P2ry1-ires-Cre
Gene: P2ry1  Location: Chr3:60910216-60916403 bp, + strand  Genetic Position: Chr3, 29.24 cM, cytoband E1
Alliance: P2ry1tm1.1(cre)Lbrl page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:223335
Parent Cell Line:  W4 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
P2ry1tm1.1(cre)Lbrl expression driven by 1 gene
 
Mutation detailsA cassette encoding IRES, Cre recombinase, and an FRT-flanked neomycin selection cassette is inserted into the mouse P2ry1 locus 3 base pairs downstream of the coding sequence stop codon. (J:223335)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: P2ry1 (mouse)
Summary of all recombinase alleles driven by P2ry1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any P2ry1 Mutation:  32 strains or lines available
References
Original:  J:223335 Chang RB, et al., Vagal Sensory Neuron Subtypes that Differentially Control Breathing. Cell. 2015 Apr 23;161(3):622-33
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory