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Glp1rtm1.1(cre)Lbrl
Targeted Allele Detail
Summary
Symbol: Glp1rtm1.1(cre)Lbrl
Name: glucagon-like peptide 1 receptor; targeted mutation 1.1, Stephen Liberles
MGI ID: MGI:5776617
Synonyms: Glp1r-ires-Cre
Gene: Glp1r  Location: Chr17:31120841-31155484 bp, + strand  Genetic Position: Chr17, 15.8 cM
Alliance: Glp1rtm1.1(cre)Lbrl page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:232319
Parent Cell Line:  W4 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Glp1rtm1.1(cre)Lbrl expression driven by 1 gene
 
Mutation detailsA cassette encoding IRES, Cre recombinase, and an FRT-flanked neomycin selection cassette is inserted into the mouse Glp1r locus 3 base pairs downstream of the coding sequence stop codon. (J:232319)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Glp1r (mouse)
Summary of all recombinase alleles driven by Glp1r.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Glp1r Mutation:  49 strains or lines available
References
Original:  J:232319 Williams EK, et al., Sensory Neurons that Detect Stretch and Nutrients in the Digestive System. Cell. 2016 Jun 30;166(1):209-21
All:  19 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory