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Igfbp5tm1(icre/ERT2)Murr
Targeted Allele Detail
Summary
Symbol: Igfbp5tm1(icre/ERT2)Murr
Name: insulin-like growth factor binding protein 5; targeted mutation 1, Stephen Murray
MGI ID: MGI:5779503
Gene: Igfbp5  Location: Chr1:72897224-72914024 bp, - strand  Genetic Position: Chr1, 36.94 cM
Alliance: Igfbp5tm1(icre/ERT2)Murr page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:259166
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Targeted (Conditional ready, Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Igfbp5tm1(icre/ERT2)Murr expression driven by 1 gene
 
Mutation details: An IRES-icre/ERT2 cassette was inserted 6 bp (AGTACT) downstream of exon 4 and an FRT flanked neomycin resistance cassette was inserted into the intron between exons 3 and 4, and this allele derived from clone 2A10. (J:259166)
Inheritance:    Not Specified
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Igfbp5 (mouse)
Summary of all recombinase alleles driven by Igfbp5.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Igfbp5 Mutation:  20 strains or lines available
References
Original:  J:259166 Seidel K, et al., Resolving stem and progenitor cells in the adult mouse incisor through gene co-expression analysis. Elife. 2017 May 5;6:e24712
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory