Pla2g12b<mpc96H> Chemically induced Allele Detail MGI Mouse (MGI:5791984)

Pla2g12b^mpc96H
Chemically induced Allele Detail

Summary

Symbol:	Pla2g12b^mpc96H
Name:	phospholipase A2, group XIIB; muta-ped-c3pde 96, Harwell
MGI ID:	MGI:5791984
Gene:	Pla2g12b Location: Chr10:59239482-59257798 bp, + strand Genetic Position: Chr10, 29.54 cM, cytoband B3
Alliance:	Pla2g12b^mpc96H page

Mutation
origin

Strain of Origin:	C57BL/6J
Project Collection:	Harwell ENU Mutagenesis

Mutation
description

Allele Type:		Chemically induced (ENU) (Not Specified)
Mutation:		Single point mutation
		Mutation details: ENU mutagenesis induced a T to A point mutation that results in the amino acid substitution of aspartic acid for tyrosine at position 66 (Y66N). (J:234901)
Inheritance:		Recessive

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Expression

In Structures Affected by this Mutation:

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Pla2g12b Mutation:	17 strains or lines available

References

Original:	J:234901 Potter PK, et al., Novel gene function revealed by mouse mutagenesis screens for models of age-related disease. Nat Commun. 2016;7:12444
All:	1 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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