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Idh3ampc201H
Chemically induced Allele Detail
Summary
Symbol: Idh3ampc201H
Name: isocitrate dehydrogenase 3 (NAD+) alpha; muta-ped-c3pde 201, Harwell
MGI ID: MGI:5792025
Synonyms: Idh3aE229K
Gene: Idh3a  Location: Chr9:54493795-54511946 bp, + strand  Genetic Position: Chr9, 29.7 cM
Alliance: Idh3ampc201H page
Mutation
origin
Strain of Origin:  C57BL/6J
Project Collection: Harwell ENU Mutagenesis
Mutation
description
Allele Type:    Chemically induced (ENU) (Not Specified)
Mutation:    Single point mutation
 
Mutation detailsENU mutagenesis induced a G to A point mutation that results in the amino acid substitution of glutamic acid with lysine at position 229 (p.E229K). (J:234901)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Idh3a Mutation:  22 strains or lines available
References
Original:  J:234901 Potter PK, et al., Novel gene function revealed by mouse mutagenesis screens for models of age-related disease. Nat Commun. 2016;7:12444
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory