Loxhd1<mpc231H> Chemically induced Allele Detail MGI Mouse (MGI:5792077)

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Loxhd1^mpc231H
Chemically induced Allele Detail

Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Summary

Symbol:	Loxhd1^mpc231H
Name:	lipoxygenase homology domains 1; muta-ped-c3pde 231, Harwell
MGI ID:	MGI:5792077
Gene:	Loxhd1 Location: Chr18:77369654-77530626 bp, + strand Genetic Position: Chr18, 52.2 cM
Alliance:	Loxhd1^mpc231H page

Mutation
origin

Strain of Origin:	C57BL/6J
Project Collection:	Harwell ENU Mutagenesis

Mutation
description

Allele Type:		Chemically induced (ENU) (Not Specified)
Mutation:		Single point mutation
		Mutation details: ENU mutagenesis induced a C to T point mutation that results in the amino acid substitution of methionine for threonine at position 1696 (T1696M). (J:234901)
Inheritance:		Recessive

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Loxhd1 Mutation:	104 strains or lines available

References

Original:	J:234901 Potter PK, et al., Novel gene function revealed by mouse mutagenesis screens for models of age-related disease. Nat Commun. 2016;7:12444
All:	1 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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