Slc17a8tm1.1(cre)Hze
Targeted Allele Detail
|
|
| Symbol: |
Slc17a8tm1.1(cre)Hze |
| Name: |
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8; targeted mutation 1.1, Hongkui Zeng |
| MGI ID: |
MGI:5792821 |
| Synonyms: |
Slc17a8-IRES2-Cre-D, Vglut3-IRES2-Cre-D |
| Gene: |
Slc17a8 Location: Chr10:89409882-89457111 bp, - strand Genetic Position: Chr10, 44.99 cM
|
| Alliance: |
Slc17a8tm1.1(cre)Hze page
|
|
|
|
| Allele Type: |
|
Targeted (No functional change, Recombinase) |
| Mutation: |
|
Insertion
|
| |
|
Slc17a8tm1.1(cre)Hze expression driven by
1 gene
Knock-in expression driven by:
|
| |
|
Mutation details: The targeting vector containes, from 5' to 3', a partial Slc17a8 sequence spanning intron 11, an frt3 site within Slc17a8 intron 11, a partial Slc17a8 exon 12 sequence up to and including the endogenous stop codon, an IRES2 sequence, a Cre recombinase, a bovine growth hormone polyA sequence, an AttB site, a PGK promoter-Neomycin resistance gene-PGK polyA cassette, an frt5 site, an mRNA splice acceptor sequence, the 3' portion of the hygromycin gene (Hygro2) with SV40 late polyA signal, and an AttP site. Chimeric mice were bred to PhiC31-expressing mice to remove the AttB/AttP-flanked sequences (PGK-Neo-polyA::frt5::RNA splice acceptor::3'hygro-polyA) and replace it with the recombined AttB/AttP site (AttL). Mice have both endogenous gene and Cre recombinase expression directed to Vglut3-expressing cells by the endogenous promoter/enhancer elements of the Slc17a8 locus.
(J:146821)
|
|
|
|
Activity: |
 Tissue activity of this recombinase allele
|
|
Driver:
|
Slc17a8
(mouse)
|
| |
|
|
|
|
| Original: |
J:146821 Allen Institute for Brain Science, Cre transgenes and knockin alleles created at the Allen Insitute for Brain Science (AIBS). MGI Direct Data Submission. 2009-04-06; |
| All: |
30 reference(s) |
|
Analysis Tools
