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Mafbtm1.1(cre)Kmm
Targeted Allele Detail
Summary
Symbol: Mafbtm1.1(cre)Kmm
Name: MAF bZIP transcription factor B; targeted mutation 1.1, Kenneth Murphy
MGI ID: MGI:5795905
Synonyms: MafB-mCherry-Cre, Mafbtm1.1(mCherry,cre)Kmm
Gene: Mafb  Location: Chr2:160205623-160208985 bp, - strand  Genetic Position: Chr2, 80.92 cM
Alliance: Mafbtm1.1(cre)Kmm page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:101977
Parent Cell Line:  JM8.N4 (ES Cell)
Strain of Origin:  C57BL/6N
Mutation
description
Allele Type:    Targeted (Recombinase, Reporter)
Mutation:    Insertion
 
Mafbtm1.1(cre)Kmm expression driven by 1 gene
 
Mutation details: A targeting construct was designed to insert a FLAG-tagged-mCherry fluorescent protein and a Cre Recombinase sequence, separated by two different viral 2A oligopeptides that mediate ribosomal skipping (P2A [from porcine teschovirus-1] and T2A [from insect Thosea asigna virus], into the coding sequence of the Mafb (v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)) gene. A frt-flanked neomycin resistance (neo) cassette was inserted 3' of the cre sequence. Resulting mice were bred to FLP1 exspressing mice to remove the neo cassette. (J:101977)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Mafb (mouse)
Summary of all recombinase alleles driven by Mafb.
 

Expression
In Mice Carrying this Mutation: 9 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Mafb Mutation:  20 strains or lines available
References
Original:  J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017;
All:  8 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory