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Xcr1tm4(cre)Ksho
Targeted Allele Detail
Summary
Symbol: Xcr1tm4(cre)Ksho
Name: chemokine (C motif) receptor 1; targeted mutation 4, Tsuneyasu Kaisho
MGI ID: MGI:5803711
Synonyms: Xcr1cre
Gene: Xcr1  Location: Chr9:123681380-123691094 bp, - strand  Genetic Position: Chr9, 74.71 cM, cytoband F4
Alliance: Xcr1tm4(cre)Ksho page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:235786
Parent Cell Line:  Bruce 4 (ES Cell)
Strain of Origin:  B6.Cg-Thy1a
Mutation
description
Allele Type:    Targeted (Null/knockout, Recombinase)
Mutations:    Insertion, Intragenic deletion
 
Xcr1tm4(cre)Ksho expression driven by 1 gene
    A cre recombinase gene and a FRT-flanked neomycin resistance cassette replaced the coding sequence. (J:235786)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Xcr1 (mouse)
Summary of all recombinase alleles driven by Xcr1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Xcr1 Mutation:  33 strains or lines available
References
Original:  J:235786 Ohta T, et al., Crucial roles of XCR1-expressing dendritic cells and the XCR1-XCL1 chemokine axis in intestinal immune homeostasis. Sci Rep. 2016 Mar 23;6:23505
All:  4 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory