Gene Expression Data
Assay Details
Assay
|
Reference:
|
J:31646
Steel KP, et al., TRP-2/DT, a new early melanoblast marker, shows that steel growth factor (c-kit ligand) is a survival factor. Development. 1992 Aug;115(4):1111-9
|
Assay type:
|
RNA in situ
|
MGI Accession ID:
|
MGI:5803803
|
Gene symbol:
|
Dct
|
Gene name:
|
dopachrome tautomerase
|
Probe:
|
clone p5A7
|
Probe preparation:
|
Antisense labelled with S35 RNA
|
Visualized with:
|
Autoradiography
|
|
Results
|
Specimen
2A:
embryonic day 9.5
(more )
Specimen
2A:
(close )
Genetic Background:
|
CBA/Ca
|
Age:
|
embryonic day 9.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS15: optic vesicle |
Present |
Regionally restricted |
2A
|
Expressed in the presumptive pigmented retinal epithelium.
|
Specimen
2B:
embryonic day 10.0
(more )
Specimen
2B:
(close )
Genetic Background:
|
CBA/Ca
|
Age:
|
embryonic day 10.0
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS16: optic cup |
Present |
Regionally restricted |
2B
|
Expressed in the presumptive pigmented retinal epithelium.
|
Specimen
2D:
embryonic day 11.5
(more )
Specimen
2D:
(close )
Genetic Background:
|
CBA/Ca
|
Age:
|
embryonic day 11.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Specimen
2F:
embryonic day 19.5
(more )
Specimen
2F:
(close )
Genetic Background:
|
CBA/Ca
|
Age:
|
embryonic day 19.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS26: Harderian gland |
Present |
Regionally restricted |
2F
|
Expressed in migratory melanocytes identified by their pigmented dendrites.
|
Specimen
3A:
embryonic day 10.0
(more )
Specimen
3A:
(close )
Genetic Background:
|
CBA/Ca
|
Age:
|
embryonic day 10.0
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS16: inner ear mesenchyme |
Present |
Regionally restricted |
3A
|
Expressed in migratory melanocytes in mesenchyme caudal to otocyst.
|
Specimen
3B:
embryonic day 10.0
(more )
Specimen
3B:
(close )
Genetic Background:
|
CBA/Ca
|
Age:
|
embryonic day 10.0
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS16: inner ear mesenchyme |
Present |
Regionally restricted |
3B
|
Expressed in melanoblasts in mesenchyme ventral to otocyst.
|
Specimen
3C:
embryonic day 11.5
(more )
Specimen
3C:
(close )
Genetic Background:
|
CBA/Ca
|
Age:
|
embryonic day 11.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS19: inner ear mesenchyme |
Present |
Regionally restricted |
3C
|
Expressed melanoblasts distributed widely in the mesenchyme around the otic vesicle.
|
Specimen
3D:
embryonic day 14.5
(more )
Specimen
3D:
(close )
Genetic Background:
|
CBA/Ca
|
Age:
|
embryonic day 14.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS22: inner ear mesenchyme |
Present |
Regionally restricted |
3D
|
Expressed in melanoblasts localised mainly to the mesenchyme above the cochlear duct.
|
Specimen
3F:
embryonic day 15.5
(more )
Specimen
3F:
(close )
Genetic Background:
|
CBA/Ca
|
Age:
|
embryonic day 15.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS23: inner ear mesenchyme |
Present |
Regionally restricted |
3F
|
Expressed in melanoblasts localised to the region of the cochlear duct that will develop into the stria vascularis.
|
Specimen
3G:
embryonic day 16.5
(more )
Specimen
3G:
(close )
Genetic Background:
|
CBA/Ca
|
Age:
|
embryonic day 16.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS24: inner ear mesenchyme |
Present |
Regionally restricted |
3G
|
Expressed in melanocytes becoming incorporated into the epithelium of the stria vascularis, particularly in the basal turn of the cochlea, which is more advanced in development than the apical turns.
|
Specimen
4A:
embryonic day 13.5
(more )
Specimen
4A:
(close )
Genetic Background:
|
CBA/Ca
|
Age:
|
embryonic day 13.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS21: inner ear mesenchyme |
Present |
Regionally restricted |
4A
|
Expressed in melanoblasts in mesenchyme ventral to otocyst.
|
Specimen
4C:
embryonic day 13.5
(more )
Specimen
4C:
(close )
Genetic Background:
|
CBA/Ca
|
Age:
|
embryonic day 13.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS21: telencephalon |
Present |
Regionally restricted |
4C
|
Expressed in the inner layer of the neuroepithelium.
|
Specimen
4E:
embryonic day 12.5
(more )
Specimen
4E:
(close )
Genetic Background:
|
CBA/Ca
|
Age:
|
embryonic day 12.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS20: telencephalon |
Present |
Regionally restricted |
4E
|
Expressed in the frontal and medial regions.
|
Specimen
5A:
embryonic day 12.0
(more )
Specimen
5A:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 12.0
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS20: telencephalon |
Present |
Regionally restricted |
5A
|
Expressed in restricted region in the whole thickness of the neurectoderm.
|
Specimen
5B:
(close )
Genetic Background:
|
Not Specified
|
Mutant Allele(s):
|
KitlSl-d/KitlSl-d
|
Age:
|
embryonic day 12.0
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS20: telencephalon |
Present |
|
5B
|
Expressed in normal pattern as in the wild-type.
|
Specimen
5C:
(close )
Genetic Background:
|
Not Specified
|
Mutant Allele(s):
|
KitlSl-d/KitlSl-d
|
Age:
|
embryonic day 14.0
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Specimen
5D:
embryonic day 14.0
(more )
Specimen
5D:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 14.0
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Specimen
5E:
(close )
Genetic Background:
|
Not Specified
|
Mutant Allele(s):
|
KitlSl-d/KitlSl-d
|
Age:
|
embryonic day 14.0
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Specimen
5F:
(close )
Genetic Background:
|
Not Specified
|
Mutant Allele(s):
|
KitlSl-d/KitlSl-d
|
Age:
|
embryonic day 12.0
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Specimen
6A:
embryonic day 11.0
(more )
Specimen
6A:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 11.0
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS18: inner ear mesenchyme |
Present |
Clusters |
6A
|
Expressed in melanocytes in mesenchyme caudal to otic vesicle around anterior cardinal vein.
|
Specimen
6B:
(close )
Genetic Background:
|
Not Specified
|
Mutant Allele(s):
|
KitlSl-d/KitlSl-d
|
Age:
|
embryonic day 11.0
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS18: inner ear mesenchyme |
Present |
|
6B
|
Expressed in melanocytes in mesenchyme caudal to otic vesicle around anterior cardinal vein, similar as in the wild-type.
|
Specimen
6C:
embryonic day 11.0
(more )
Specimen
6C:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 11.0
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS18: inner ear mesenchyme |
Present |
Clusters |
6C
|
Expressed in melanoblasts around the developing cochlear duct.
|
Specimen
6D:
(close )
Genetic Background:
|
Not Specified
|
Mutant Allele(s):
|
KitlSl-d/KitlSl-d
|
Age:
|
embryonic day 11.0
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS18: inner ear mesenchyme |
Present |
|
6D
|
Fewer positive cells at this location than in controls, and rarely appear close to the cochlear duct.
|
Specimen
6E:
embryonic day 12.0
(more )
Specimen
6E:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 12.0
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS20: inner ear mesenchyme |
Present |
Regionally restricted |
6E
|
Expressed in melanoblasts around the developing cochlea.
|
Specimen
6F:
(close )
Genetic Background:
|
Not Specified
|
Mutant Allele(s):
|
KitlSl-d/KitlSl-d
|
Age:
|
embryonic day 12.0
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Specimen
not shown:
embryonic day 12.5
(more )
Note: Camera lucida drawing was shown in 4F.
Specimen
not shown:
(close )
Genetic Background:
|
CBA/Ca
|
Age:
|
embryonic day 12.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Note:
|
Camera lucida drawing was shown in 4F.
|
Structure |
Level |
Pattern |
Image |
Note |
TS20: telencephalon |
Strong |
Regionally restricted |
|
Expressed in the frontal and medial regions.
|
Specimen
not shown:
postnatal newborn
(more )
Specimen
not shown:
(close )
Genetic Background:
|
CBA/Ca
|
Age:
|
postnatal newborn
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS27: hair follicle |
Strong |
Regionally restricted |
|
Expressed in melanocytes (melanin-containing cells).
|
TS27: mouse |
Strong |
Regionally restricted |
|
Expressed in melanocytes (melanin-containing cells).
|
TS27: skin |
Strong |
Regionally restricted |
|
Expressed in melanocytes (melanin-containing cells).
|
Specimen
not shown:
embryonic day 10.0
(more )
Note: Summarized in Table 1.
Specimen
not shown:
(close )
Genetic Background:
|
CBA/Ca
|
Age:
|
embryonic day 10.0
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Note:
|
Summarized in Table 1.
|
Structure |
Level |
Pattern |
Image |
Note |
TS16: embryo mesenchyme |
Present |
Regionally restricted |
|
Expressed in migratory melanoblasts.
|
Specimen
not shown:
embryonic day 10.5
(more )
Note: Summarized in Table 1.
Specimen
not shown:
(close )
Genetic Background:
|
CBA/Ca
|
Age:
|
embryonic day 10.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Note:
|
Summarized in Table 1.
|
|