Col6a6 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:208903 Pan TC, et al., A mouse model for dominant collagen VI disorders: heterozygous deletion of Col6a3 Exon 16. J Biol Chem. 2014 Apr 11;289(15):10293-307
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:5804163
Gene symbol:	Col6a6
Gene name:	collagen, type VI, alpha 6

Antibody:	collagen VI alpha6 antibody
Detection system:	Cy3

Results

6A a6(VI) +/+ ©

Specimen 6A alpha6(VI) +/+: embryonic day 17.0 (more

)

Structure	Level	Image
TS25: skeletal muscle	Present	6A a6(VI) +/+
TS25: dermis	Absent	6A a6(VI) +/+
TS25: rib	Absent	6A a6(VI) +/+

6A a6(VI) +/d16 ©

Specimen 6A alpha6(VI) +/d16: embryonic day 17.0; Col6a3^tm2.1Chu/Col6a3⁺ (more

)

Structure	Level	Image
TS25: skeletal muscle	Present	6A a6(VI) +/d16
TS25: dermis	Absent	6A a6(VI) +/d16
TS25: rib	Absent	6A a6(VI) +/d16

6A a6(VI) d16/d16 ©

Specimen 6A alpha6(VI) d16/da6: embryonic day 17.0; Col6a3^tm2.1Chu/Col6a3^tm2.1Chu (more

)

Structure	Level	Image
TS25: skeletal muscle	Present	6A a6(VI) d16/d16
TS25: dermis	Absent	6A a6(VI) d16/d16
TS25: rib	Absent	6A a6(VI) d16/d16

6B a6(VI) +/+ ©

Specimen 6B alpha6(VI) +/+: embryonic day 17.0 (more

)

Structure	Level	Image
TS25: diaphragm	Present	6B a6(VI) +/+
TS25: pleura	Present	6B a6(VI) +/+
TS25: skeletal muscle	Present	6B a6(VI) +/+
TS25: lung	Absent	6B a6(VI) +/+

6B a6(VI) +/d16 ©

Specimen 6B alpha6(VI) +/d16: embryonic day 17.0; Col6a3^tm2.1Chu/Col6a3⁺ (more

)

Structure	Level	Image
TS25: diaphragm	Present	6B a6(VI) +/d16
TS25: pleura	Present	6B a6(VI) +/d16
TS25: skeletal muscle	Present	6B a6(VI) +/d16
TS25: lung	Absent	6B a6(VI) +/d16

6B a6(VI) d16/d16 ©

Specimen 6B alpha6(VI) d16/d16: embryonic day 17.0; Col6a3^tm2.1Chu/Col6a3^tm2.1Chu (more

)

Structure	Level	Image
TS25: diaphragm	Present	6B a6(VI) d16/d16
TS25: pleura	Present	6B a6(VI) d16/d16
TS25: skeletal muscle	Present	6B a6(VI) d16/d16
TS25: lung	Absent	6B a6(VI) d16/d16

6C a6(VI) +/+ ©

Specimen 6C alpha6(VI) +/+: postnatal week 2 (more

)

Structure	Level	Pattern	Image	Note
TS28: tail	Present	Regionally restricted	6C a6(VI) +/+	Expression in tendon sheath and muscle. No expression in tendon fascicles, nerve and vertebrae.
TS28: tail vertebra	Present		6C a6(VI) +/+

6C a6(VI) +/d16 ©

Specimen 6C alpha6(VI) +/d16: postnatal week 2; Col6a3^tm2.1Chu/Col6a3⁺ (more

)

Structure	Level	Pattern	Image	Note
TS28: tail	Present	Regionally restricted	6C a6(VI) +/d16	Expression in tendon sheath and muscle. No expression in tendon fascicles, nerve and vertebrae.
TS28: tail vertebra	Absent		6C a6(VI) +/d16

6C a6(VI) d16/d16 ©

Specimen 6C alpha6(VI) d16/d16: postnatal week 2; Col6a3^tm2.1Chu/Col6a3^tm2.1Chu (more

)

Structure	Level	Pattern	Image	Note
TS28: tail	Present	Regionally restricted	6C a6(VI) d16/d16	Expression in tendon sheath and muscle. No expression in tendon fascicles, nerve and vertebrae.
TS28: tail vertebra	Absent		6C a6(VI) d16/d16

7A a6(VI) +/+ ©

Specimen 7A alpha6(VI) +/+: postnatal month 1 (more

)

Structure	Level	Pattern	Image	Note
TS28: quadriceps femoris muscle	Present		7A a6(VI) +/+	Comparable levels of expression in all 3 genotypes.

Specimen 7A alpha6(VI) +/d16: postnatal month 1; Col6a3^tm2.1Chu/Col6a3⁺ (more

)

Structure	Level	Pattern	Image	Note
TS28: quadriceps femoris muscle	Present		7A a6(VI) +/d16	Comparable levels of expression in all 3 genotypes.

Specimen 7A alpha6(VI) d16/d16: postnatal month 1; Col6a3^tm2.1Chu/Col6a3^tm2.1Chu (more

)

Structure	Level	Pattern	Image	Note
TS28: quadriceps femoris muscle	Present		7A a6(VI) d16/d16	Comparable levels of expression in all 3 genotypes.

9_a6(VI) +/+ ©

Specimen 9 alpha6(VI) +/+: postnatal month 6 (more

)

Structure	Level	Pattern	Image	Note
TS28: quadriceps femoris muscle	Ambiguous		9_a6(VI) +/+

Specimen 9 alpha6(VI) +/d16: postnatal month 6; Col6a3^tm2.1Chu/Col6a3⁺ (more

)

Structure	Level	Pattern	Image	Note
TS28: quadriceps femoris muscle	Present	Regionally restricted	9_a6(VI) +/d16	Expression increased around some myofibers.

Specimen 9 alpha6(VI) d16/d16: postnatal month 6; Col6a3^tm2.1Chu/Col6a3^tm2.1Chu (more

)

Structure	Level	Pattern	Image	Note
TS28: quadriceps femoris muscle	Present	Regionally restricted	9_a6(VI) d16/d16	Expression increased around some myofibers.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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