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Nfatc1em2(GFP/cre)Bzsh
Endonuclease-mediated Allele Detail
Summary
Symbol: Nfatc1em2(GFP/cre)Bzsh
Name: nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1; endonuclease-mediated mutation 2, Bin Zhou
MGI ID: MGI:5804181
Synonyms: Nfatc1-GFP, Nfatc1tm5.1(GFP/cre)Bz
Gene: Nfatc1  Location: Chr18:80649420-80756286 bp, - strand  Genetic Position: Chr18, 53.66 cM, cytoband E4
Alliance: Nfatc1em2(GFP/cre)Bzsh page
Mutation
origin
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Endonuclease-mediated (Recombinase, Reporter)
Mutation:    Insertion
 
Nfatc1em2(GFP/cre)Bzsh expression driven by 1 gene
 
Mutation details: The line was generated by inserting a 2A peptide sequence and a cDNA encoding a GFP-Cre fusion protein into the last common coding exon of Nfatc1 by homologous recombination using the CRISPR/Cas9 technology. (J:231966)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Nfatc1 (mouse)
Summary of all recombinase alleles driven by Nfatc1.
 

Expression
In Mice Carrying this Mutation: 12 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nfatc1 Mutation:  49 strains or lines available
References
Original:  J:231966 Zhang H, et al., Genetic lineage tracing identifies endocardial origin of liver vasculature. Nat Genet. 2016 May;48(5):537-43
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory