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Slntm1.1(cre)Krc
Targeted Allele Detail
Summary
Symbol: Slntm1.1(cre)Krc
Name: sarcolipin; targeted mutation 1.1, Kenneth R Chien
MGI ID: MGI:5804671
Synonyms: SLN-Cre
Gene: Sln  Location: Chr9:53757535-53761133 bp, + strand  Genetic Position: Chr9, 29.24 cM, cytoband C
Alliance: Slntm1.1(cre)Krc page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:233948
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout, Recombinase)
Mutations:    Insertion, Intragenic deletion
 
Slntm1.1(cre)Krc expression driven by 1 gene
 
Mutation details: Exon 2 of the Sln locus including the 1st ATG was replaced with Cre recombinase and FRT flanked neomycin resistant cassette by homologous recomibination. The neo cassette was removed in the final line. The knocked in cre gene is expressed by the Sln promoter in atrial liniage cells starting at day E10.0. (J:233948)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Sln (mouse)
Summary of all recombinase alleles driven by Sln.
 

Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sln Mutation:  11 strains or lines available
References
Original:  J:233948 Nakano H, et al., Cardiac origin of smooth muscle cells in the inflow tract. J Mol Cell Cardiol. 2011 Feb;50(2):337-45
All:  6 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/09/2024
MGI 6.24 		The Jackson Laboratory