Tg(Vim-cre/ERT2)#Rshw
Transgene Detail
|
|
| Symbol: |
Tg(Vim-cre/ERT2)#Rshw |
| Name: |
transgene insertion, Robert F Schwabe |
| MGI ID: |
MGI:5804689 |
| Synonyms: |
Vim-CreER |
| Transgene: |
Tg(Vim-cre/ERT2)#Rshw Location: unknown
|
| Alliance: |
Tg(Vim-cre/ERT2)#Rshw page
|
|
|
|
| Transgene Type: |
|
Transgenic (Inducible, Recombinase) |
| Inducer: |
|
tamoxifen |
| Mutation: |
|
Insertion
|
| |
|
Tg(Vim-cre/ERT2)#Rshw expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Note |
| Not Specified |
Vim |
|
|
| |
|
Mutation details: A cre/ERT2 cassette was inserted at the ATG codon in exon 1 of the Vim gene in the BAC by recombineering methods. The neo cassette was removed by flippase, and the modified BAC construct was injected into fertilized CBA x C57BL/6J oocytes. One of three founders was crossed to reporter mice for analyses. One line shows strong cre-recombinase expression induction after tamoxifen injection, however specific line number(s) used for the experiments are not given.
(J:231716)
|
|
|
|
Activity: |
 Tissue activity of this recombinase allele
|
|
Driver:
|
Vim
(species not specified)
|
| |
|
|
| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
|
| Original: |
J:231716 Troeger JS, et al., Deactivation of hepatic stellate cells during liver fibrosis resolution in mice. Gastroenterology. 2012 Oct;143(4):1073-83.e22 |
| All: |
5 reference(s) |
|
Analysis Tools
