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Tg(Gata4*G2-cre)#Roja
Transgene Detail
Summary
Symbol: Tg(Gata4*G2-cre)#Roja
Name: transgene insertion, Anabel Rojas
MGI ID: MGI:5805214
Synonyms: G2-GATA4Cre, Gata4-G2-Cre
Transgene: Tg(Gata4*G2-cre)#Roja  Location: unknown  
Alliance: Tg(Gata4*G2-cre)#Roja page
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Gata4*G2-cre)#Roja expression driven by 1 gene
 
Mutation detailsA transgene consisting of an 817 bp fragment containin the conserved region, CR2, of the G2 Gata4 enhancer, 642 bp fragment containing minimal promoter from the mouse Mef2c gene, the cre cDNA, and SV40 splice and polyA signal sequence was generated. A total of 4 founder lines with similar patterns of cre activity were created. Line numbers were not specified in the original reference. (J:231985)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Gata4 (mouse)
Summary of all recombinase alleles driven by Gata4.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 28 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:231985 Delgado I, et al., GATA4 loss in the septum transversum mesenchyme promotes liver fibrosis in mice. Hepatology. 2014 Jun;59(6):2358-70
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory